Cardiac magnetic resonance evidence of diffuse myocardial fibrosis in patients with mitral valve prolapse
نویسندگان
چکیده
Background Diffuse myocardial fibrosis can be assessed by cardiac magnetic resonance (CMR) using the myocardial longitudinal relaxation time constant (T1). Mitral valve prolapse (MVP) is a common valvulopathy with known arrhythmic complications and in-vitro evidence of overexpression of pro-fibrotic TGF-beta. Papillary muscle fibrosis has been described in MVP, but the potential association of MVP with diffuse myocardial fibrosis is unknown. This association is important as it may increase our future understanding of ventricular arrhythmias in MVP.
منابع مشابه
Diffuse myocardial fibrosis in patients with mitral valve prolapse and ventricular arrhythmia.
OBJECTIVE We aimed to investigate the association of diffuse myocardial fibrosis by cardiac magnetic resonance (CMR) T1 with complex ventricular arrhythmia (ComVA) in mitral valve prolapse (MVP). METHODS A retrospective analysis was performed on 41 consecutive patients with MVP referred for CMR between 2006 and 2011, and 31 healthy controls. Arrhythmia analysis was available in 23 patients wi...
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